Tmod3 regulates polarized epithelial cell morphology

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Tmod3 regulates polarized epithelial cell morphology.

Although the role of the actin cytoskeleton in morphogenesis of polarized epithelial sheets is generally accepted as centrally important, the regulation of actin dynamics in this process remains unclear. Here, we show that the pointed-end capping protein Tmod3 contributes to epithelial cell shape within confluent monolayers of polarized epithelial cells. Tmod3 localizes to lateral cell membrane...

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ژورنال

عنوان ژورنال: Journal of Cell Science

سال: 2007

ISSN: 1477-9137,0021-9533

DOI: 10.1242/jcs.011445